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NMS 873
CAS No. 1418013-75-8
NMS 873 ( VCP Inhibitor III )
Catalog No. M11746 CAS No. 1418013-75-8
NMS-873 is a potent, selective allosteric VCP/p97 inhibitor with IC50 value of 20 nM (Wild Type, 1 mM ATP).
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 35 | In Stock |
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| 5MG | 55 | In Stock |
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| 10MG | 101 | In Stock |
|
| 25MG | 188 | In Stock |
|
| 50MG | 339 | In Stock |
|
| 100MG | 521 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNMS 873
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NoteResearch use only, not for human use.
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Brief DescriptionNMS-873 is a potent, selective allosteric VCP/p97 inhibitor with IC50 value of 20 nM (Wild Type, 1 mM ATP).
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DescriptionNMS-873 is a potent, selective allosteric VCP/p97 inhibitor with IC50 value of 20 nM (Wild Type, 1 mM ATP).
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SynonymsVCP Inhibitor III
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PathwayProteasome/Ubiquitin
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Targetp97
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Recptorp97
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1418013-75-8
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Formula Weight520.67
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Molecular FormulaC27H28N4O3S2
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Purity>98%(HPLC)
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SolubilityDMSO: 100 mg/mL (192.06 mM)
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SMILESO=S(C1=CC=C(C2=CC=C(OCC3=NN=C(SC4CCCC4)N3C5=CC=CN=C5)C=C2C)C=C1)(C)=O
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Chemical Name3-(3-(cyclopentylthio)-5-(((2-methyl-4'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)oxy)methyl)-4H-1,2,4-triazol-4-yl)pyridine.
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Magnaghi P, et al. Nat Chem Biol. 2013, 9(9), 548-556.
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