Cart
sales@molnova.com
NMS 873
CAS No. 1418013-75-8
NMS 873( VCP Inhibitor III )
Catalog No. M11746 CAS No. 1418013-75-8
NMS-873 is a potent, selective allosteric VCP/p97 inhibitor with IC50 value of 20 nM (Wild Type, 1 mM ATP).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 35 | In Stock |
|
| 5MG | 55 | In Stock |
|
| 10MG | 101 | In Stock |
|
| 25MG | 188 | In Stock |
|
| 50MG | 339 | In Stock |
|
| 100MG | 521 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNMS 873
-
NoteResearch use only, not for human use.
-
Brief DescriptionNMS-873 is a potent, selective allosteric VCP/p97 inhibitor with IC50 value of 20 nM (Wild Type, 1 mM ATP).
-
DescriptionNMS-873 is a potent, selective allosteric VCP/p97 inhibitor with IC50 value of 20 nM (Wild Type, 1 mM ATP).
-
In Vitro——
-
In Vivo——
-
SynonymsVCP Inhibitor III
-
PathwayProteasome/Ubiquitin
-
Targetp97
-
Recptorp97
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1418013-75-8
-
Formula Weight520.67
-
Molecular FormulaC27H28N4O3S2
-
Purity>98% (HPLC)
-
SolubilityDMSO: 100 mg/mL (192.06 mM)
-
SMILESO=S(C1=CC=C(C2=CC=C(OCC3=NN=C(SC4CCCC4)N3C5=CC=CN=C5)C=C2C)C=C1)(C)=O
-
Chemical Name3-(3-(cyclopentylthio)-5-(((2-methyl-4'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)oxy)methyl)-4H-1,2,4-triazol-4-yl)pyridine.
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Magnaghi P, et al. Nat Chem Biol. 2013, 9(9), 548-556.
molnova catalog
related products
-
LC-1028
LC-1028 (LC1028) is a novel potent selective, covalent and irreversible inhibitor of p97 (valosin-containing protein).
-
TPX-0046
TPX-0046 is a RET inhibitor designed to overcome resistance to Selpercatinib and Pralsetinib.
-
NMS 873
NMS-873 is a potent, selective allosteric VCP/p97 inhibitor with IC50 value of 20 nM (Wild Type, 1 mM ATP).
